Red blood cell (RBC) aging in health, disease and storage is of considerable interest. 2020 Jun 25. doi: 10.1002/anie.202006381. Red blood cells (RBCs) are part of nonimmune blood-lineage cells derived from hematopoietic stem cells.

Anchoring supramolecular polymers to human red blood cells by combining dynamic covalent and non-covalent chemistries Angew Chem Int Ed Engl .

Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells Author links open overlay panel Gurnit Kaur a b 1 Warda Javed b c 1 Olena Ponomarenko d Kamran Shekh b c Diane P. Swanlund b c Janet R. Zhou a b Kelly L. Summers d e Angela Casini f g Margot Wenzel f Joseph R. Casey b c h Emmanuelle Cordat b … Further research may identify them as blood group systems. 1-4 Thus, a considerable effort has been made to develop new therapies for the treatment of anemia. Red blood cells account for more than 80% of cells in the human body, and their primary role is to shuttle oxygen from our lungs to our organs, the authors wrote. This antibody is associated with WBC. These three groups are antigens with shared characteristics but do not meet the International Society of Blood Transfusion (ISBT) definition of a human blood group system. Anemia continues to exert tremendous burdens to human health. It is associated more with tissue antibodies than red blood cells.

During aging/storage, RBCs lose water, 2,3-bisphosphosphoglyceric acid, ATP, proteins, Hb and vesicles leading to decreasing cell volume, surface charge and increasing density. “Red blood cells’ innate ability to transfer attached pathogens to immune cells has only recently been discovered, and this study unlocks the door to an exciting array of future developments in the field of using human cells for disease treatment and prevention.” A ‘check me out’ signal